THE SCIENCE BEHIND PRO ANABOLIC™
Pro-Anabolic™ was specifically developed as the next-generation replacement for old Anabolics, replicating their effects by directly targeting the very same master molecular pathways that regulate musculoskeletal performance.
A WORLD-FIRST STRATEGY THAT NOT ONLY DELIVERS SUPERIOR EFFICACY BUT ALSO ELIMINATES ALL SIDE EFFECTS.
Between 2019 and 2023, the most significant research ever conducted into the mechanisms of anabolic and catabolic muscle metabolism was completed by world-leading scientists and sports medical laboratories.
THE R&D JOURNEY /////////////
The Human Genome Project (2022) identified the genes regulating muscle; Larson at the Mayo Clinic (2019) uncovered the structural mechanisms underlying muscle fibers; and Lopez (2023) revealed perhaps the most critical data in the quest for state-of-the-art muscle-building technology—the sub-cellular root causes of human muscle aging.
In 2025, this research culminated in an unprecedented breakthrough: Pro-Anabolic™.
The result is the evolutionary successor to traditional anabolics—and unquestionably the most significant advance in sports science history
A MILESTONE IN SPORTS SCIENCE
001
BIO-HACKING THE SECRET BIOCHEMICAL FORMULA UNDERPINNING MUSCLE CELL GROWTH.
THE FUTURE OF MUSCULAR ENHANCEMENT IS HERE
NPB = MPS – MPB
So what does this equation mean?
Net Protein Balance (muscle mass) =
Muscle Protein Synthesis (Anabolism) – Muscle Protein Breakdown (Catabolism).
Think of it as a muscle equation: to grow muscle at the cellular level, more building than breaking down is required—a ‘positive Net Protein Balance.’
Achieve a positive value, and muscle has no option but to grow.
It’s the non-negotiable law of thermodynamics that can’t be cheated—yet is ignored by other supplements.
002
INCREASING PROTEIN SYNTHESIS:
THE FUNDAMENTAL BUILDING BLOCKS OF MUSCLE
To hack this biochemical balance, your body must synthesize the proteins myosin and actin—the intracellular building blocks of muscle. If your body cannot do this, building muscle is impossible.
Think of muscle cells as balloons: filling them with air causes them to expand. The same happens to muscles—when they fill with protein, they grow in size.
Scientists call this process protein synthesis. Without an increase in protein uptake in muscle, growth simply cannot occur—and crucially, it’s a mechanism that traditional supplements cannot significantly influence.
003
NATURAL MYOSTATIN MUTATION RESULTING IN EXTREME MUSCULAR GROWTH.
GTCA-TAGC-GCAT-ATGC
GTCA-TAGC-GCAT-ATGC
CAGT-GGCT-CTAG-TACG
CAGT-GGCT-CTAG-TACG
TAGC-ACGT-GTCA-GGCT
TAGC-ACGT-GTCA-GGCT
CGTA-TAGC-AGCT-CGTA
CGTA-TAGC-AGCT-CGTA
THE WORLDS FIRST NUTRACEUTICAL TO BIOHACK MUSCLE GROWTH AT THE MOLECULAR LEVEL
While ingredients like BCAAs aim to boost muscle protein synthesis at the metabolic level, they fail to target key molecular pathways such as mTOR and Myostatin, which fundamentally regulate protein synthesis and muscle growth at the master genetic level—a biological “butterfly effect.”
To develop Pro Anabolic, we required a deeper understanding of the cellular and molecular mechanisms behind muscle, which were still not fully understood.
CRACKING THE GENETIC
CODE OF MUSCLE
Exploiting breakthroughs in decoding the genetic foundations of human performance—culminating in the landmark 2023 Human Genome Project—scientists at Future Pharma have for the first time in history identified the molecular pathways that control musculoskeletal development.
Pro-Anabolic™ directly targets these master on/off switches, initiating muscle-building chain reactions at the source—from ATF4, which regulates muscle loss, to Decorin, which inhibits muscle-limiting myostatin—ushering in a new era in bodybuilding with unprecedented growth potential.
004THE NEXT GENERATION OF TESTOSTERONE-LIKE REPLICATING MOLECULES
The persistent problem with traditional anabolic hormones lies in their indirect artifical activation of molecular pathways via synthetic, harmful hormones.
Pro-Anabolic™ pioneers a radical approach—one that directly and naturally targets the same pathways - with the same potency.
Leveraging Google’s AlphaFold breakthrough in AI-powered receptor simulations, Pro-Anabolic™ introduces a new class of ingredients known as nutrigenomic signalling molecules. These revolutionary compounds simulate the protein-synthesis-elevating effects of testosterone the deepest levels of gene expression—all with inherently zero side effects.
THIS APPROACH DELIVERS THE SAME BIOLOGICAL ACTIVITY AS TESTOSTERONE, COMBINING THE POTENCY OF TRADITIONAL ANABOLICS WITH THE SAFETY OF SUPPLEMENTS /////////
005EXPANDING THE ANABOLIC WINDOW WITH CLINICALY PROVEN COMPOUNDS.
The two pivotal pathways underlying muscle growth are mTOR-ATF4 and the Myostatin-Decorin axis ; one signals an increase in protein synthesis, while the other signals a decrease.
Pro-Anabolic™ utilizes the strongest known molecules to elevate anabolic mTOR while suppressing catabolic Myostatin, expanding the crucial anabolic “window” where muscle growth occurs¹⁷ by a combined 195%¹⁵,¹⁰—engineering the biological holy grail of cellular environments for muscular development.
↑120%
+mTOR PROTEIN SYNTHESIS
Clinical trials on Pro-Anabolic’s (+)-20-Hydroxyecdysone compound, conducted at Biotech Center, Cook College, recorded a 400% increase in mTOR gene expression⁶—the master ON switch of muscle growth—elevating anabolic muscle protein synthesis by a startling 120%.¹⁰
↓75%
-PROTEIN DEGRDATON
At the University of Bonn, Germany, researchers trialing (+/-)-sulforaphane observed a 50% reduction in myostatin activity¹⁵—the master OFF switch of muscle loss—resulting in a remarkable 75%¹⁵ suppression of catabolic muscle degradation.
WELCOME TO THE FUTURE OF MUSCLE ENHANCEMENT
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WELCOME TO THE FUTURE OF MUSCLE ENHANCEMENT ////////////
006
THE FIRST BIOPHARMACEUTICAL TO ENHANCE THE FULL ECOSYSTEM UNDERPINNING MUSCLE METABOLISM.
Contrary to popular belief, anabolic metabolism is not a singular process but involves multiple mechanisms—satellite stem cells, mitochondria, neuromuscular motoneurons, and more—all functioning as an interconnected ecosystem¹⁶
Conventional biopharma, based on outdated reductionist biology, is inherently limited, as it targets only isolated aspects of a larger network.
Leveraging breakthroughs in systems biology, Pro-Anabolic™ addresses them all: a patented cocktail of 15 pharmaceutical-grade ingredients targeting every factor underpinning muscle metabolism, enabling complete lean muscular enhancement.
EXPLORED PRO ANABOLICS SYSTEMS APPROACH TO MUSCULAR ENHANCMENT WHITEPAPER
007 
FEEL PRO ANABOLIC WORKING FROM DAY ONE
As soon as you start taking Pro-Anabolic™, you’ll feel it start working. In fact, during a human clinical trial at the Mexican Escuela Superior de Medicina del Instituto Politécnico Nacional, participants saw gains of 7% in just 7 days⁹, with optimal results seen after completing the full four-month course.
When can I expect to see results?
GET THE FULL COURSE WITH 40% SAVING >
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1Month 1: Gene Expression, Growth Factor and Anabolic Signaling Enhancement Lays the Foundation for Enhanced Muscular Development
The Initial Catalyst for New Muscle Formation, Growth, and Adaptation.
Muscle growth is orchestrated by growth factors and hormones that signal cellular growth and regulate every stage of development. From fibroblast growth factors (FGF) that activate satellite cells, transforming them into mature muscle fibers, to anabolic signaling that promotes protein synthesis and prevents catabolic protein breakdown.
Pro-Anabolic™ optimizes this entire process by enhancing the body’s natural biological systems to produce growth factors and anabolic hormones at the master molecular level, amplifying muscle growth gene expression without unwanted side effects.
Initiates Satellite Cell Development: Fuels muscle growth by activating stem cells, transforming them into new muscle fibers.
Enhanced Muscle Development: Growth factors, including IGF-1, FGF (fibroblast growth factor), and testosterone signaling, elevate protein synthesis—the building blocks of muscle.
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2 Inducing SatelliteStem Cells to Develop into Fully Grown New Muscle Cells for Increased Muscle Mass
Fundamentally Enhancing the Potential for Muscle Growth
The development of new muscle begins with satellite stem cells. Upon activation, these cells multiply, laying the foundation for the formation of new muscle fibers and enhancing the body’s raw capacity for muscle growth and regeneration.
Pro-Anabolic™ stimulates the creation of new muscle cells, known as hyperplasia—previously believed to be impossible after birth. By targeting key factors such as fibroblast growth factors (FGFs) and insulin-like growth factors (IGFs), and activating genetic pathways like WNT, MyoD, and Myf5, Pro-Anabolic™ increases the baseline level of muscle cells, allowing users to transcend genetic limitations.
Increased Satellite Muscle Cell Count: The generation of satellite cells that develop into muscle fibers unlocks the full capacity for muscle development.
Greater Muscle Growth and Regeneration: A Higher Number of muscle cells structurally enhance muscle tissue, improving overall performance.
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3 Month THREE: Formation of Muscle Fibers: Type 1 (Slow) and Type 2 (Fast) for Enhanced Explosive Strength and Endurance
Fusion of Muscle Satellite Cells into Fully Matured Muscle Fibers Drives Functional Strength Gains
Once satellite cells are formed, they develop into fully functional muscle fibers capable of contraction and fuse with existing fibers, increasing their anatomical size—resulting in real worl strength and performance improvements.
Pro-Anabolic™ activates this process by boosting the expression of critical growth factors like myogenin and MRF4, essential for the maturation of muscle fibers. Additionally, it modulates pathways that inhibit satellite cell development, expanding the muscle's structural capacity and growth potential.
Improved Muscle Function: As these cells fuse, they form mature muscle fibers capable of contraction, enhancing endurance and overall muscle performance.
Enhanced Muscle Strength: As new fibers are added and existing ones become more robust, noticeable gains in muscle strength and power are achieved.
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4 By the end of the optimal four-month course, your body will undergo dramatic changes—muscle fibers synthesizing to near-inhuman proportions and strength.
The Ongoing Synthesis of Muscle Fibers: Establishing a New Baseline for Progressive Anatomical Enhancement
Once new muscle fibers are formed, they become more permanent as the body adapts to its heightened state of muscular development. Their ongoing growth relies on increased protein synthesis—the essential building blocks of muscle.
Pro-Anabolic™ optimizes this process by activating the mTOR pathway, the key driver of muscle protein synthesis, while simultaneously suppressing the myostatin pathway, which inhibits muscle growth. This dual-action approach amplifies protein production and prevents muscle breakdown, ensuring continuous muscle gains and long-lasting results.
Muscle Fiber Growth: Hypertrophy, or the enlargement of muscle fibers, leads to increased cross-sectional muscle mass and definition.
Increased Strength: As muscle fibers grow, they generate more force, resulting in enhanced strength and performance.
Metabolic Benefits: Increased muscle mass boosts basal metabolic rate, supporting weight management.
008BIOENGINEERING THE STRONGEST LEGAL MOLECULES UNAVAILABLE ELSEWHERE.
Conventional supplements rely on the same generic ingredients that suffer from either low efficacy or unwanted side effects.
Instead, Pro-Anabolic™ uses AI simulations to biohack next-generation molecules, structurally modified at the atomic level to enhance desired effects while eliminating unwanted ones.
Supplied at fully effective clinical dosages and suspended in nanoparticles to deliver bioactive compounds directly to target cells without degradation. With a half-life aligned to anabolic circadian rhythms, Pro-Anabolic™ stands without equal.
PRO ANABOLIC IS A PATENTED COCKTAIL OF THESE 100% LEGAL, CLINICAL PROVEN, COMPOUND EXTRACTS AT CLINICALLY RELEVANT DOSAGES:
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RESVERATROL
Harvard's Breakthrough Anti-Aging And Performance-Enhancing Molecule: Undergoing Clinical Trials With Nasa And The Us Military To Create Enhanced Humans, With Preclinical Trials Demonstrating A Remarkable 56-80% Greater Exercise Performance.
Cellular Performance And Longevity
ATPNAD is fundamental to life, serving as a critical energy source for our cells. Yet, starting in our twenties, its levels begin to decline, reaching less than half of youthful levels by middle age. Research from MIT has shown that Resveratrol restores and elevates ATP+ levels, activating the newly discovered SIRT1 pathway, a crucial regulator of cellular metabolism, performance, and aging.
Transforming Muscle Cells into Super Muscle Cells
Developed by Dr. Sinclair at Harvard Medical School, Resveratrol is undergoing human clinical trials for its remarkable ability to enhance humans and combat aging. Testing is underway by the US Special Forces to create ‘super soldiers,’ while NASA is harnessing its regenerative properties to enable astronaut missions to Mars.
Resveratrol offers far-ranging benefits to performance:
56-80% athletic enhancement
Boosting mitochondrial function to increase energy
Promoting stem cell regeneration to grow new muscle
Facilitating autophagy to remove old senescent cells
Inhibiting muscle-degrading fat infiltration
Elevating overall body metabolism
The most striking effect, however, emerged in Harvard's preclinical trials, where Resveratrol-treated animals demonstrated between 56% and 80% greater exercise capacity. These animals managed to run 430 meters compared to 240 meters for their untreated peers.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Second-generation Resveratrol increase NADATP levels up to 200-300%, while “normal” Resveratrol can only increase NADATP levels by 40%
Molecular Target
SIRTUIN 1-7 . Specifically, studies have shown that Resveratrol can enhance SIRT1 activity by 40% to 100%,Key Cellular Process
ATPNAD plays a crucial role in the functioning of mitochondria, the metabolic powerhouses in our body's cells.Pro Anabolic Clinical Trial Equivalent Dose
400mgRESEARCH
Paul F. Glenn Center for the Biological Mechanisms of Aging, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA -
Mimicking 'Vampire' Blood Rejuvenation Harnessed by PayPal Co-Founder and Trump Financial Backer: New Molecular Technique from Stanford Enhances Muscle Growth, Stem Cell Regeneration, and Vascularization—Clinical Trials at University of Geneva Show 80% Strength Increase and 21% Endurance Boost
Vampire Blood Parabiosis and Performance:
Disregarding vampire legends, the concept of rejuvenating aged blood with young blood dates back to 1950s experiments at Cornell University. These experiments involved parabiosis—the connection of the circulatory systems of old and young mice to induce youth-like regeneration.
The concept regained attention when the U.S. biotech startup Ambrosia explored it for human longevity, gaining notoriety when Peter Thiel, PayPal co-founder and Donald Trump financial backer, utilized their ‘fountain of youth’ blood transfusions for anti-aging.
Rejuvenating Blood at the Molecular Level:
In 2013, Stanford University identified two key molecular targets in blood, GDF11 and VCAM1, responsible for the benefits of transfusions. These proteins, similar to catabolic myostatin - increase with age and are instrumental in performance loss and its rejuvenation.
3 5 4'-trihydroxystilbene [Resveratrol] when used with the correct protocol, can effectively reproduce these benefits. According to research from the University of Geneva, resveratrol modulates the activity of GDF11 and VCAM1. These molecules play crucial roles in several key processes:
Inhibiting muscle-wasting catabolism
Promoting muscle stem cell regeneration
Remodeling blood vessel vasculature
Mitigating inflammation and oxidation
Reduces Blood Glucose and fat synthesis
x1.2 - 1.8 strength gains
Significantly, research from the University of Alberta has validated Resveratrol's striking muscular enhancement benefits, recording increased time to aerobic exhaustion by 21% and anaerobic strength gains from 1.2 to 1.8 times.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Pterostilbene is a methylated stilbene molecule with structural similarity to resveratrol, the difference being two methoxy groups on the pterostilbene molecule that replace hydroxy groups on the resveratrol molecule that is both is more potent and also much better absorbed.
Molecular Targets
GDF11 - Muscle Growth InhibitorVCAM1- inflammation and oxidative stress.
Key Cellular Process
Stem cell regeneration and cellular senescence.Pro Anabolic Clinical Trial Equivalent Dose
3000mg
4g/kg bodyweight in animal studies
RESEARCH
Dolinsky, Vernon W et al. “Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats.” The Journal of physiology vol. 590,11 (2012): 2783-99. doi:10.1113/jphysiol.2012.230490
Sinha, Manisha et al. “Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.” Science (New York, N.Y.) vol. 344,6184 (2014): 649-52. doi:10.1126/science.1251152
Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell. 2013 May 9;153(4):828-39. doi: 10.1016/j.cell.2013.04.015. PMID: 23663781; PMCID: PMC3677132.
Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ, Lee RT. Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation. Circ Res. 2016 Apr 1;118(7):1125-41; discussion 1142. doi: 10.1161/CIRCRESAHA.116.308391. PMID: 27034275; PMCID: PMC4818972.
Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ, Lee RT. Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation. Circ Res. 2016 Apr 1;118(7):1125-41; discussion 1142. doi: 10.1161/CIRCRESAHA.116.308391. PMID: 27034275; PMCID: PMC4818972.
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Iowa University's Clinical Breakthrough: Dual Anabolic and Anti-catabolic Recomposition Agent dramatically Boosts Strength by 30%, Muscle Mass by 10%, and reduces Fat, as Featured by Dr. Rhonda Patrick on the Joe Rogan Podcast
Targeting the Root Cause of Muscle Loss
As we grow older, we lose strength and muscle mass. However, the cause of age-related muscle weakness and atrophy has remained a mystery.
Research funded by the US Government at Iowa University has identified the ATF4 pathway as the first known molecular cause of age-related muscle atrophy and found that Ursolic acid blunts this activity. This alters gene expression in skeletal muscle, leading to significantly increased protein synthesis, strength, and muscle mass.
Building Muscle and Inhibiting Fat
Acting as a natural growth factor, Ursolic acid significantly influences muscle development at the cellular level, displaying both anabolic and anti-catabolic properties that are uniquely capable of increasing muscle while simultaneously reducing fat.
Anti Catabolic
Pro Anabolic
Metabolic Fat repositioning
80% elevated Muscle Protein Synthesis
22.8%increased IGF expression
Ursolic acid boosts IGF-1 expression by 22.8%, facilitating the most instrumental process in muscle hypertrophy by initiating the key steps of satellite cell recruitment into new fibers.
Additionally, it elevates mTOR-ATF4 muscle protein synthesis activity by 80%, compared to just 10-20% achieved by the popular supplement beta-alanine.The most striking effects were published in the Journal of Biological Chemistry, recording an increase in muscle mass by 10 percent and, more importantly, increased muscle quality, or strength, by 30 percent.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Next generation UA derivative ; Alpha-tomatine [αTM] - is nearly 10-fold more potent and 5-fold more orally bioavailable
Molecular Target
IGF-1 [22.8% increase] Growth Factor
ATF4 Muscle AgingKey Cellular Process
Muscle fiber Hypertrophy (growth)Pro Anabolic Clinical Trial Equivalent Dose
450mgRESEARCH
Ebert, Scott M et al. “Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.” The Journal of biological chemistry vol. 290,42 (2015): 25497-511. doi:10.1074/jbc.M115.681445
.^Bang HS1, Seo DY2, Chung YM3, Oh KM4, Park JJ5, Arturo F6, Jeong SH2, Kim N2, Han J2Ursolic Acid-induced elevation of serum irisin augments muscle strength during resistance training in menKorean J Physiol Pharmacol.(2014 Oct)
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Breakthrough Natural Sterone-like Molecule: Clinical Trials Conducted with WADA Show 2kg Muscle Growth and 19.4% Strength Increase, Rivaling Traditional Anabolics While Remaining Safe and Legal
A New Era of Anabolics
Since the Designer Anabolic Steroid Control Act of 2014, which rightfully prohibited dangerous and illegal anabolics, the market has lacked truly effective testosterone-like muscular enhancement.
Futures Ecdysterone 20E derivative introduces a next-generation natural anabolic replacement. Comparable in potency to traditional steroids and structurally similar to testosterone, 20E activates muscle growth by mimicking testosterone signaling with a remarkable 200-300% increase in mTOR molecular pathway activation, the master "ON" switch for muscle growth—elevating protein synthesis by 120%, compared to just 10.8% achieved with leucine.
Mimics Testosterone Signaling
Non Androgenic Anabolic Agent
Induces Satellite Stem cells into new muscle cells
2KG Muscle Gain
19.4% Strength Gain
Validated Human Enhancement by WADA (World Anti-Doping Agency)
This efficacy was clinically validated by WADA, which studied 20E due to its striking anabolic-like yet legal efficacy, achieving effects parallel to testosterone but without artificial hormonal manipulation and its androgenic side effects.
Human Clinical Studies at the German Sport University demonstrated 20E's remarkable capacity to increase muscle mass by 2 kilograms and elevate strength by 19.4% in just 10 weeks, rivaling the anabolic impact of potent yet antiquated androgens like Dbol and DHT. Described by Rutgers University's Biotech Center as “behaving similar to anabolic steroids, putatively without the androgenic effect,” 20E represents the future of anabolic enhancement.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Hungarian chemists, associated with the University of Szeged, reported in 2015 that poststerone, a kind of stripped version of ecdysterone, had a 50% greater anabolic effect in test tubes than ecdysterone.
Molecular Target
mTOR - AKT - Muscle Synthesis - x3- 5-fold activationKey Cellular Process
x120% Muscle protein synthesisPro Anabolic Clinical Trial Equivalent Dose
100mgRESEARCH
Isenmann, Eduard et al. “Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans.” Archives of toxicology vol. 93,7 (2019): 1807-1816. doi:10.1007/s00204-019-02490-x
Issaadi, Halima Meriem et al. “Side-chain cleaved phytoecdysteroid metabolites as activators of protein kinase B.” Bioorganic chemistry vol. 82 (2019): 405-413. doi:10.1016/j.bioorg.2018.10.049
Gorelick-Feldman J, Cohick W, Raskin IEcdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cellsSteroids.(2010 Oct)
Gorelick-Feldman J, Maclean D, Ilic N, Poulev A, Lila MA, Cheng D, Raskin IPhytoecdysteroids increase protein synthesis in skeletal muscle cellsJ Agric Food Chem.(2008 May 28)
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Transcend Genetic Muscle Potential: Induce Satellite Stem Cells into Brand New Muscle Cells and Deactivate Catabolic Myostatin by 50%.
/////////Muscle Tissue Development: Hypertrophy growth vs Hyperplasia multiplication
Muscle tissue can develop through two fundamentally different processes:
1.Hypertrophy: The conventional approach enhances the size of existing muscle fibers, inherently limited by the body's original anatomical structure. This is the sole method pursued by conventional supplements.
2.Hyperplasia: A transformative increase in the actual number of muscle fibers, once believed impossible after infancy.Transcending Genetic Limitations with Cutting-edge Stem Cell Technology
50% Catabolic Myostatin inhibition
40% Greater Satellite cell viability into new muscle fibers
Research led by molecular biologists at the University of Naples has unveiled the revolutionary potential of isothiocyanates for hyperplasia muscle multiplication. This compound can activate the newly discovered WNT molecular pathway, transformation of satellite stem cells within muscle cells into brand new, additional muscle fibers.
Further discoveries at the University of Bonn in Germany reveal that isothiocyanates block the catabolic myostatin signaling pathway, the master inhibitor of muscle development within satellite cells, by a remarkable 50%. This breakthrough boosts the potential stem cell count by 40%, enabling athletes for the very first time to surpass their genetic constraints, exceed their potential, and develop brand new muscle.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Pro Anabolic contains 6-MSHI (6-methylsulfinylhexyl isothiocyanate)- an engineered derivative of sulforaphane that is more readily absorbed and induces cellular enzymatic reactions more potently than standard Sulforaphane.
Molecular Targets
Myostatin - decreases catabolic muscle suppression by 50%WNT - activated enhancing stem cell proliferation and differentiation by 40%
Cellular Process
Hyperplasia - brand new muscle cell formation
Pro Anabolic Clinical Trial Equivalent Dose
200-400 mg per dayRESEARCH
Fan, Huitao et al. “Sulforaphane causes a major epigenetic repression of myostatin in porcine satellite cells.” Epigenetics vol. 7,12 (2012): 1379-90. doi:10.4161/epi.22609
Zhang, Rui et al. “Sulforaphane Enhanced Proliferation of Porcine Satellite Cells via Epigenetic Augmentation of SMAD7.” Animals : an open access journal from MDPI vol. 12,11 1365. 26 May. 2022, doi:10.3390/ani12111365
Morimitsu, Yasujiro et al. “A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.” The Journal of biological chemistry vol. 277,5 (2002): 3456-63. doi:10.1074/jbc.M110244200
Zanichelli, Fulvia et al. “Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect.” Age (Dordrecht, Netherlands) vol. 34,2 (2012): 281-93. doi:10.1007/s11357-011-9231-7
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A new direct molecular method enhances the body’s own biological systems that regulate hormone production—resulting in a 70% increase in testosterone at the root precursor stage, with zero side effects.
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Historic Shortcomings in Testosterone Enhancement
Testosterone signaling is essential for creating a muscle-building anabolic environment. Traditional methods relied upon artificial, synthetic testosterone manipulation, which led to significant androgenic side effects. In contrast, Apigenin introduces a new approach that targets the molecular pathway that upregulates testosterone at its natural production stage, combining potent elevation while exhibiting zero androgenic side effects.Biohacks natural testosterone production
Anti Catabolic action
70% Greater Free Testosterone
54% Muscle Growth
Natural 70% Testosterone Production Increase at the Molecular Level
Researchers at Texas Tech University, exploring anti-aging solutions to combat declining testosterone levels, discovered that Apigenin, a naturally occurring compound, significantly boosts testosterone production. It does this by upregulating the Steroidogenic Acute Regulatory (StAR) molecular target, the key regulator at the precursor stage of cholesterol's conversion into testosterone, resulting in a remarkable eightfold natural increase in testosterone synthesis by Leydig cells. This increase occurs without any side effects, as it harnesses our body's natural processes.
Preclinical Trials Demonstrate 54% Muscle Growth
Further studies by the University of Science and Technology in South Korea underscored Apigenin's potential for real-world musculoskeletal enhancement. Preclinical trials revealed a significant 54% increase in quadriceps muscle weight and an 18% improvement in running distance, demonstrating the verified connection between elevated testosterone and enhanced performance.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
7-hydroxyflavone Apigenin analogue with hydroxyl group at position 7 of the flavone nucleus (0.2–0.7 mM) were more potent than apigenin (1.2–2.9 mM), [Sanderson, J Thomas et al]
Molecular Target
Steroidogenic Acute Regulatory [Star] ProteinCellular Process
Anabolic Growth Factor SignalingPro Anabolic Clinical Trial Equivalent Dose
7-hydroxyflavone apigenin analogue hydroxyl group at position 7 of the flavone nucleus (0.2–0.7 mM) were more potent than apigenin (1.2–2.9 mM), [Sanderson, J Thomas et al]
RESEARCH
Li, Wei et al. “Effects of apigenin on steroidogenesis and steroidogenic acute regulatory gene expression in mouse Leydig cells.” The Journal of nutritional biochemistry vol. 22,3 (2011): 212-8. doi:10.1016/j.jnutbio.2010.01.004Jang, Young Jin et al. “Apigenin enhances skeletal muscle hypertrophy and myoblast differentiation by regulating Prmt7.” Oncotarget vol. 8,45 78300-78311. 16 Sep. 2017, doi:10.18632/oncotarget.20962
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Next-Generation Aromatase Inhibitor Developed at Beckman Research Institute, California: Reduces Catabolic Estrogen by 80.5%, Promoting Fat Free Muscle Mass
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Pharmaceutical Grade Anti-catabolic Estrogenic Inhibition
Creating an optimal anabolic environment that promotes lean muscle growth involves not only increasing testosterone-driven anabolism but also reducing estrogen-driven catabolism that inhibits muscle growth and promotes fat accumulation.70.4% - 80.5% Catabolic Estrogen Suppression
Suppresses Muscle Degrading Cortisol
Promotes Anabolic Signaling
Landmark research from the Beckman Research Institute in California has unveiled the potent anti-estrogenic properties of OPC-3. This extract significantly inhibits aromatase, the enzyme responsible for converting testosterone into estradiol, by 70.4% - 80.5%. Such inhibition not only surpasses conventional supplements but also rivals pharmaceutical-grade compounds like Andro-3,5-diene-7,17-dione, highlighting OPC-3’s exceptional potency.
Molecular-Level Action for a Lean Muscle Environment
OPC-3 operates at the underlying molecular level, combining safety with efficacy. It targets crucial pathways by suppressing the aromatase enzyme (CYP1A1/2) that converts testosterone into estrogens, and the glucocorticoid receptor, preventing cortisol—a hormone that promotes fat accumulation and muscle damage—from binding.
Ultimately, OPC-3 rebalances anabolic to catabolic signaling to favor anabolism—promoting a lean muscular environment and mitigating a fat-promoting, muscle-damaging estrogenic one.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Oligomeric Proanthocyanidins Complex
GSE, an extract from grape seeds, consists of 75 percent proanthocyanidins - of these procyanidin B dimers are the most active ones harnessed in Pro Anabolic.
Molecular Targets
aromatase enzyme (CYP1A1/2)
glucocorticoid receptor (GR)Key Cellular Process
Next-Generation Aromatase Inhibitor Developed at Beckman Research Institute, California: Reduces Catabolic Estrogen by 80.5%, Promoting Fat Free Muscle MassPharmaceutical Grade Anti-catabolic Estrogenic Inhibition
Creating an optimal anabolic environment that promotes lean muscle growth involves not only increasing testosterone-driven anabolism but also reducing estrogen-driven catabolism that inhibits muscle growth and promotes fat accumulation.
70.4% - 80.5% Catabolic Estrogen Suppression
Suppresses Muscle Degrading Cortisol
Promotes Anabolic Signaling
Landmark research from the Beckman Research Institute in California has unveiled the potent anti-estrogenic properties of OPC-3. This extract significantly inhibits aromatase, the enzyme responsible for converting testosterone into estradiol, by 70.4% - 80.5%. Such inhibition not only surpasses conventional supplements but also rivals pharmaceutical-grade compounds like Andro-3,5-diene-7,17-dione, highlighting OPC-3’s exceptional potency.
Molecular-Level Action for a Lean Muscle Environment
OPC-3 operates at the underlying molecular level, combining safety with efficacy. It targets crucial pathways by suppressing the aromatase enzyme (CYP1A1/2) that converts testosterone into estrogens, and the glucocorticoid receptor, preventing cortisol—a hormone that promotes fat accumulation and muscle damage—from binding.
Ultimately, OPC-3 rebalances anabolic to catabolic signaling to favor anabolism—promoting a lean muscular environment and mitigating a fat-promoting, muscle-damaging estrogenic one.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Oligomeric Proanthocyanidins Complex
GSE, an extract from grape seeds, consists of 75 percent proanthocyanidins - of these procyanidin B dimers are the most active ones harnessed in Pro Anabolic.
Molecular Targets
aromatase enzyme (CYP1A1/2)
glucocorticoid receptor (GR)Key Cellular Process
Anti Estrogenic, Anti Catabolic AromatasePro Anabolic Clinical Trial Equivalent Dose
100mgRESEARCH
Kijima, Ikuko et al. “Grape seed extract is an aromatase inhibitor and a suppressor of aromatase expression.” Cancer research vol. 66,11 (2006): 5960-7. doi:10.1158/0008-5472.CAN-06-0053
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Direct Molecular Activation of the EPO Pathway: Naturally Harnessing Lance Armstrong’s Infamous Tour de France secret to Boost Oxygen Delivery to muscle cells, Clinically Proven to Enhance Aerobic Performance by 60%
////////////Oxygen is the Lifeblood of Performance
Erythropoietin (EPO) became notorious due to the Lance Armstrong doping scandal in the Tour de France. EPO enhances red blood cell production, significantly boosting the body's capacity to transport oxygen to muscles and other tissues, thereby improving aerobic performance in athletes.
Historically, methods to elevate EPO involved synthetic derivatives, which led to significant side effects.
Enhancing Oxygen Delivery from the Molecular Level
Researchers at the Hong Kong University of Science and Technology discovered that Astragalus compounds facilitate increased EPO synthesis via the natural activation of the HIF-1alpha gene at the molecular level, increasing hemoglobin production and thereby significantly enhancing oxygen delivery to cells.
Elevates Oxygen Delivery
Protects telomere Shortening
Remodels Blood Supply
60% Greater Endurance
Furthermore, it promotes the development of new blood vasculature, allowing athletes to remodel their blood supply and enhance tissue oxygenation—an anatomical advantage that could persist even after the compound is discontinued.
Remarkable findings from Tzu-Shao Yeh at Taipei Medical University highlight this approach's efficacy, with a landmark study showing a 60% improvement in endurance training performance from Astragalus administration.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
When the researchers repeated the experiment with the astragaloside flavonoids, it emerged that all four boosted the synthesis of EPO. The best EPO-booster was calycosin-7-O-beta-D-glucoside
Molecular TargetsHypoxia-Inducible Factors (HIF-1alpha gene)
Key Cellular Process
Blood oxygenating hemoglobin productionPro Anabolic Clinical Trial Equivalent Dose
200mg
RESEARCH
Yeh, Tzu-Shao et al. “Astragalus membranaceus improves exercise performance and ameliorates exercise-induced fatigue in trained mice.” Molecules (Basel, Switzerland) vol. 19,3 2793-807. 3 Mar. 2014, doi:10.3390/molecules19032793
Zheng, Ken Y Z et al. “Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1α.” Journal of agricultural and food chemistry vol. 59,5 (2011): 1697-704. doi:10.1021/jf104018
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Pioneering Mitochondrial Enhancement Developed with Maverick Russian Biochemist Vladimir Skulachev: Supercharging Cellular Energy with Preclinical Trials demonstrating 39% Greater Performance Capacity
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Enhancing Sub Cellular Mitochondrial Metabolism
Mitochondria are the fundamental energy-producing organelles in muscle cells that power their performance. However, in doing so, they generate significant oxidative stress and inflammation, causing cellular damage leading to diminished performance and aging.
SkQ1, a derivative of the well-known coenzyme Q10, is the brainchild of Russian biochemist Vladimir Skulachev. Developed in collaboration with Lomonosov Moscow State University and Stockholm University, SkQ1 targets sub-cellular pathways PGC1a and Nrf2, scavenging free radicals and initiating anti-inflammatory processes, thus preserving mitochondrial integrity and enhancing their metabolic efficiency.
Enhances Mitochondrial energy output
Anti Inflammatory
Anti Oxidant
39% Greater Performance Capacity
double the lifespan of test animals.
Clinical Evidence of Performance Enhancement
SkQ1 enhances muscular performance by enabling mitochondria to produce more energy for muscles to utilize while mitigating the byproducts generated by exercise, facilitating faster recovery and regeneration.
In groundbreaking pre-clinical studies conducted in St. Petersburg by Skulachev, SkQ1 was shown to double the lifespan of test animals. The most relevant performance research was conducted by Swedish scientists at Uppsala University on the anti-fatigue effect of lead Q10 coenzymes, demonstrating a striking improvement in endurance capacity by 39%.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
SkQ1 [ SKulachev ions No.1 ]
SkQ1 is a variant of the well-known co-enzyme Q10. Engineered as a synthetic molecule that combines plastoquinone (a quinone found in chloroplasts) with a decyltriphenylphosphonium (TPP) cation. The TPP cation facilitates its targeting to mitochondria due to the mitochondrial membrane potential with superior bioavailability, potency, and efficacy
Molecular Targets
PGC1a - Mitochondrial Biogenesis
NRf2 - Anti InflammatoryKey Cellular Process
Mitochondria ROS [reactive oxygen species]Pro Anabolic Clinical Trial Equivalent Dose
100mg
RESEARCH
The Wenner-Gren Institute, Stockholm University,
Anisimov, Vladimir N et al. “Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents.” Aging vol. 3,11 (2011): 1110-9. doi:10.18632/aging.100404
Uppsala University, Uppsala, Sweden
Fu, Xin et al. “Antifatigue effect of coenzyme Q10 in mice.” Journal of medicinal food vol. 13,1 (2010): 211-5. doi:10.1089/jmf.2009.0049
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Groundbreaking Human Clinical Trial with Medicina del Instituto: Achieves 16.6% Myostatin Inhibition, Boosting Strength by 7% in Just 7 Days
////////////Targeting Catabolic Myostatin for Unlimited Muscle Growth
Inhibiting myostatin, the master genetic 'off' switch that restricts muscle growth, leads to extraordinary muscle development. This phenomenon is naturally observed in double-muscled bulls and humans with genetic mutations, making myostatin inhibition a long-sought 'holy grail' in bodybuilding.
Historically, synthetic myostatin inhibitors like follistatin faced challenges due to activity throughout the entire body - not just muscle cells, leading to undesirable side effects. Success required finding a way to increase the body’s own follistatin production. Promising treatments like Wyeth Pharmaceuticals’ Myo-029 were halted after Pfizer's acquisition.+
Human Clinical Trials Record 7% Strength Gain in Just 7 Days
While a few natural molecules are known to interact with myostatin signaling, none had been tested in human clinical trials until now. Research with the Escuela Superior de Medicina del Instituto Politécnico Nacional demonstrated that (-)-epicatechin significantly reduces myostatin levels by 16.6% and naturally increases follistatin by 49.2% - a key biological ratio underpinning muscle development , resulting in a 7% strength increase after just seven days.Suppresses Catabolic Myostatin
Elevates Blood supply Vasodilation
7% strength gain in just 7 days (Human Study)
Reduces myostatin levels by 16.6%
Significant increases in treadmill performance (∼50%)
Enhanced in situ muscle fatigue resistance (∼30%)
EPI research is redefining the genetic limits of muscle growth. It is the only compound ever demonstrated to both naturally increase follistatin production and decrease myostatin, a ratio that serves as a key pharmacodynamic biomarker of muscle growth.
SPECIFICATION
Future Pharmaceuticals Enhanced Derivative
Procyanidin B2: A dimeric compound composed of two epicatechin units allows for a synergistic effect - amplifying the biological actions compared to a single unit in (-)-epicatechin. more extensive interactions with proteins and enzymes involved in myostatin regulation
Molecular Targets
Myostatin gene (MSTN)Key Cellular Process
Anti Catabolic Protein DegradationPro Anabolic Clinical Trial Equivalent Dose
1 mg of (-)-epicatechin per kg of body weight, twice a day. This translated to about 75 mg of (-)-epicatechin, twice a day, for a total daily dose of 150 mg.
RESEARCH
Gutierrez-Salmean, Gabriela et al. “Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation.” The Journal of nutritional biochemistry vol. 25,1 (2014): 91-4. doi:10.1016/j.jnutbio.2013.09.007
Xu M, Chen X, Huang Z, Chen D, Chen H, Luo Y, Zheng P, He J, Yu J, Yu B. Procyanidin B2 Promotes Skeletal Slow-Twitch Myofiber Gene Expression through the AMPK Signaling Pathway in C2C12 Myotubes. J Agric Food Chem. 2020 Feb 5;68(5):1306-1314. doi: 10.1021/acs.jafc.9b07489. Epub 2020 Jan 27. PMID: 31957433.
Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15;589(Pt 18):4615-31. doi: 10.1113/jphysiol.2011.209924. Epub 2011 Jul 25. PMID: 21788351; PMCID: PMC3208228.
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A. Yes, Pro-Anabolic™ is 100% guaranteed safe and free from all unwanted, androgenic side effects. It targets the same molecular pathways that control muscle growth as traditional androgens, but utilizes next-generation natural cell signaling molecules that mimic testosterone's effects with inherent safety.
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A. Thanks to Pro-Anabolic™'s safe, non-androgenic, and non-testosterone-manipulating action, it is suitable for both men and women seeking the strongest bioceutical for extreme muscular enhancement that remains both safe and legal.
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A: No. Post Cycle Therapy (PCT) is typically required after using traditional synthetic testosterone agents because introducing unnatural testosterone causes the body to halt its own production. PCT helps bridge the gap between stopping testosterone use and the body restarting natural production. However, Pro-Anabolic™ elevates the body's own biological anabolic signaling at the molecular level without manipulating artificial testosterone, so PCT is not needed.
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A: Pro-Anabolic™ is taken orally, once a day—no injections are required. It’s best taken in the morning to align with the body's natural anabolic circadian rhythms, which peak during that time.
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A: Yes, Pro-Anabolic™ is supported by independent, published clinical research data that demonstrates its high effectiveness. For details and references to these trials, please visit our research page.
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A: The optimal course is four months to experience the full spectrum of results and the complete developmental cycle of new muscle cell formation (hyperplasia) and muscle growth (hypertrophy).
A discount is available on the 4-month stack for this reason. Click here for more details: [link]. -
A: Results are long-lasting—typically measured in years, not months. This is due to Pro-Anabolic™'s ability to fundamentally remodel the underlying cellular architecture that supports muscle at the molecular level, along with reprogramming epigenetic muscle memory.
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A: Yes. Pro-Anabolic™ is 100% legal. All ingredients have been carefully selected and engineered to be the strongest legally permitted, adhering to WADA (World Anti-Doping Agency) regulations, the United States Designer Anabolic Steroid Control Act of 2014, and manufactured in FDA-approved labs.
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A: Results vary depending on individual factors, but clinical and preclinical trials have demonstrated significant outcomes. Participants experienced an average of 2kg muscle growth (German Sports University, WADA), a 30% increase in strength and a 10% increase in lean muscle mass (University of Iowa), along with a 56–80% improvement in athletic performance (Harvard Medical School), - within the first cycle.
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A: Each bottle provides a 30-day supply when taken once daily.
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A: Yes. We are confident in Pro-Anabolic™'s high efficacy, which is why we can offer a full, no-questions-asked refund policy. Simply return the product, even if used, for a complete refund
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A: Yes—every purchase includes a free concierge service with unlimited, personalized support from our performance experts.
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A: While it’s theoretically possible to combine other supplements with Pro-Anabolic™, this should not be necessary. The results achieved with Pro-Anabolic™ alone are more than sufficient.
Additionally, using multiple products simultaneously can make it difficult to determine which product is delivering the results, along with the potential for unwanted interactions. -
A: Yes, but not as commonly advised. Popular bodybuilding advice promotes pure protein shakes to optimize the building of new muscle proteins. However, much of the increase in protein uptake in muscle is due to a reduction in the breakdown rate rather than an increase in new protein synthesis.
Therefore, consuming only protein supplements is not optimal. It’s best to combine protein (20-40g) post training with slow-release carbohydrates and healthy, non-saturated fats to provide the necessary fuel and prevent muscle breakdown.
[K. D. Tipton, A. A. Ferrando, ‘Improving muscle mass: response of muscle metabolism to exercise, nutrition and anabolic agents’. Essays Biochem. 44, 85–98 (2008).] -
A: Slow Release: Mainstream advice promotes fast-release protein to quickly enter muscle cells for faster repair and growth. However, the latest research shows that slow-release protein from the gut to the bloodstream is more beneficial, rather than focusing solely on rapid absorption into the muscle cells.
A rapid spike in amino acids doesn't give cellular processes enough time to adapt and facilitate a smooth flow of protein into muscle cells. Instead, the shock sends a signal that the body has too many amino acids. This triggers emergency pathways, leading the body to dispose of the excess in the spleen (catabolism) rather than using it for muscle growth (anabolism).
The result is muscle loss, not gain, making slow-release protein essential for sustained muscle development.
Macnaughton LS, Wardle SL, Witard OC, McGlory C, Hamilton DL, Jeromson S, Lawrence CE, Wallis GA, Tipton KD. The response of muscle protein synthesis following whole-body resistance exercise is greater following 40 g than 20 g of ingested whey protein. Physiol Rep. 2016 Aug;4(15):e12893. doi: 10.14814/phy2.12893. PMID: 27511985; PMCID: PMC4985555. -
No. Prohormones are simply substances that the body converts into testosterone and still come with the same side effects.
Pro-Anabolic™, however, directly activates the upstream gene expression pathways that drive muscle growth, bypassing all hormonal routes entirely.
EXPERIENCE THE FUTURE OF MUSCULAR ENHANCEMENT TODAY
Future Pharmaceuticals Lead Scientist concluded that what Pro-Anabolic™ ultimately does is bypass the traditional androgenic route of activating molecular pathways, instead utilizing direct and natural nutrigenomic gene expression enhancement. This approach boosts protein synthesis while minimizing breakdown, achieving a positive net protein balance in the body.
This action expands the anabolic window, promoting hypertrophic growth and hyperplasia, the multiplication of muscle cells—ultimately inducing dramatic muscle development.
GET READY TO GROW MORE MUSCLE IN THE NEXT FEW WEEKS THAN THE LAST FEW YEARS.